For television presenter Lisa Wartberg (Heike Makatsch) her job is the most important thing in life. This changes only when her mother Maria (Katharina Thalbach) loses her memory after an accident and suddenly has only one thought left in her head, namely, that she has never been to New York.
The resolute lady flees from the hospital and smuggles herself as a stowaway onboard a cruise liner destined for New York. Lisa goes in search of her mother, with her makeup artist Fred (Michael Ostrowski) in tow, and actually finds Maria – but the ship leaves before the three of them can disembark. But that turns out to be luck in misfortune.